FOSPHENYTOIN (fos FEN i toyn) is used to control seizures in certain types of epilepsy. It can help to prevent seizures occurring during or after surgery.
This medicine is for injection into a vein or muscle or for infusion into a vein. It is given by a health-care professional in a hospital or clinic setting.
Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as newborns for selected conditions, precautions do apply.
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
dark yellow or brown urine
difficulty breathing, wheezing or shortness of breath
double vision or uncontrollable and rapid eye movement
fever, sore throat
loss of seizure control
poor control of body movements or difficulty walking
redness, blistering, peeling or loosening of the skin, including inside the mouth
unusual bleeding or bruising, pinpoint red spots on skin
worsening of mood, thoughts or actions of suicide or dying
yellowing of the eyes or skin
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
excessive hair growth on the face or body
Do not take this medicine with any of the following medications:
certain medicines used to treat HIV infection or AIDS that are given in combination with cobicistat
This medicine may also interact with the following medications:
- aspirin and aspirin-like medicines
certain medicines for blood pressure like nifedipine, nimodipine, and verapamil
certain medicines for cancer
certain medicines for cholesterol like atorvastatin, simvastatin, and fluvastatin
certain medicines for depression, anxiety, or psychotic disturbances
certain medicines for fungal infections like ketoconazole and itraconazole
certain medicines for irregular heart beat like amiodarone and quinidine
certain medicines for seizures like carbamazepine, phenobarbital, and topiramate
certain medicines for stomach problems like cimetidine and omeprazole
female hormones, like estrogens and birth control pills
medicines that relax muscles for surgery
medicines used to treat HIV infection or AIDS
narcotic medicines for pain
phenothiazines like chlorpromazine, mesoridazine, prochlorperazine, thioridazine
St. John's Wort
steroid medicines like prednisone or cortisone
sulfonamides like sulfamethoxazole or sulfasalazine
supplements like folic acid or vitamin D
This does not apply.
This drug is given in a hospital or clinic and will not be stored at home.
They need to know if you have any of these conditions:
an alcohol abuse problem
blood disorders or disease
heart disease, low blood pressure
suicidal thoughts, plans, or attempt; a previous suicide attempt by you or a family member
an unusual or allergic reaction to phenytoin, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
Visit your doctor or health care professional for regular checks on your progress. Your doctor or health care professional may schedule regular blood tests, because this medicine needs careful monitoring. Do not stop using this medicine suddenly. This increases the risk of seizures. Because your condition and the use of this medicine carry some risk, it is a good idea to carry an identification card, necklace or bracelet with details of your condition, medications and doctor or health care professional.
You may feel dizzy or drowsy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. To reduce the risk of dizzy or fainting spells, do not sit or stand up quickly, especially if you are an older patient. Alcohol can make you more dizzy, increase flushing and may cause rapid heartbeats. Avoid alcoholic drinks.
This medicine can cause unusual growth of gum tissues. Visit your dentist regularly. Problems can arise if you need dental work, and in the day to day care of your teeth. Try to avoid damage to your teeth and gums when you brush or floss your teeth.
The use of this medicine may increase the chance of suicidal thoughts or actions. Pay special attention to how you are responding while on this medicine. Any worsening of mood, or thoughts of suicide or dying should be reported to your health care professional right away.