MIDAZOLAM (MID ay zoe lam) is a benzodiazepine. It is used to cause relaxation or sleep before surgery and to block memory of the procedure.
This medicine is for injection into a muscle or vein. It is given by a health care professional in a hospital or clinic setting.
Talk to your pediatrician regarding the use of this medicine in children. While this medicine may be prescribed for children for selected conditions, precautions do apply.
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
disorientation or hallucinations during recovery
fast, irregular heartbeat
involuntary eye and muscle movements
pain, redness, or irritation at site where injected
pain, tingling, numbness in the hands or feet
signs and symptoms of low blood pressure like dizziness; feeling faint or lightheaded, falls; unusually weak or tired
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
loss of memory of events just before, during, and after use
trouble sleeping, nightmares
Do not take this medicine with any of the following medications:
certain antiviral medicines for HIV or AIDS
certain medicines for fungal infections like ketoconazole and itraconazole
narcotic medicines for cough
This medicine may also interact with the following medications:
antihistamines for allergy, cough and cold
calcium channel blockers like diltiazem and verapamil
certain antibiotics like clarithromycin, erythromycin, rifampin
certain medicines for anxiety or sleep
certain medicines for depression, like amitriptyline, fluoxetine, sertraline
certain medicines for seizures like carbamazepine, phenobarbital, primidone
general anesthetics like lidocaine, pramoxine, tetracaine
medicines that relax muscles for surgery
narcotic medicines for pain
phenothiazines like chlorpromazine, mesoridazine, prochlorperazine, thioridazine
This does not apply.
This drug is given in a hospital or clinic and will not be stored at home.
They need to know if you have any of these conditions:
an alcohol or drug abuse problem
bipolar disorder, depression, psychosis, or other mental health condition
lung or breathing disease
seizures or a history of seizures
an unusual or allergic reaction to midazolam, other benzodiazepines, benzyl alcohol, foods, dyes, or preservatives
pregnant or trying to get pregnant
Your condition will be closely monitored while you receive this medicine.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.
If you are taking another medicine that also causes drowsiness, you may have more side effects. Give your health care provider a list of all medicines you use. Your doctor will tell you how much medicine to take. Do not take more medicine than directed. Call emergency for help if you have problems breathing or unusual sleepiness.