PROCHLORPERAZINE (proe klor PER a zeen) helps to control severe nausea and vomiting. This medicine is also used to treat schizophrenia. It can also help patients who experience anxiety that is not due to psychological illness.
This medicine is for injection into a muscle, or injection or infusion into a vein. It is given by a health care professional in a hospital or clinic setting.
Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 2 years of age for selected conditions, precautions do apply.
Side effects that you should report to your doctor or health care professional as soon as possible:
abnormal production of milk in females
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
breast enlargement in both males and females
chest pain, fast or irregular heartbeat
dark yellow or brown urine
dizziness or fainting spells
drooling, shaking, movement difficulty, or rigidity
fever, chills, sore throat
involuntary or uncontrollable movements of the eyes, mouth, head, arms, and legs
stomach area pain
unusually weak or tired
unusual bleeding or bruising
yellowing of skin or eyes
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
difficulty passing urine
Do not take this medicine with any of the following medications:
antidepressants like citalopram, escitalopram, fluoxetine, paroxetine, and sertraline
tricyclic antidepressants like amitriptyline, clomipramine, imipramine, nortriptyline and others
This medicine may also interact with the following medications:
medicines for pain
This does not apply.
This drug is given in a hospital or clinic and will not be stored at home.
They need to know if you have any of these conditions:
blood disorders or disease
liver disease or jaundice
uncontrollable movement disorder
an unusual or allergic reaction to prochlorperazine, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
Your condition will be monitored carefully while you are receiving this medicine.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.
This medicine can reduce the response of your body to heat or cold. Dress warm in cold weather and stay hydrated in hot weather. If possible, avoid extreme temperatures like saunas, hot tubs, very hot or cold showers, or activities that can cause dehydration such as vigorous exercise.
This medicine can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and use sunscreen. Do not use sun lamps or tanning beds/booths.
Your mouth may get dry. Chewing sugarless gum or sucking hard candy, and drinking plenty of water may help. Contact your doctor if the problem does not go away or is severe.