CONJUGATED ESTROGENS (CON ju gate ed ESS troe jenz) is a mixture of female hormones. It is used to treat abnormal bleeding from the uterus caused by a hormonal imbalance. This medicine may also be used for a short period of time to increase your body's estrogen levels.
This medicine is for injection into a vein, or injection into a muscle. It is given by a health care professional in a hospital or clinic setting.
A patient package insert for the product will be given with each prescription and refill. Read this sheet carefully each time. The sheet may change frequently.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
breakthrough bleeding and spotting
breast enlargement, tenderness, or abnormal production of milk
changes in vision
confusion or forgetfulness
general ill feeling or flu-like symptoms
leg, arm, or groin pain
loss of appetite, nausea
right upper belly pain
unusually weak or tired
yellowing of the eyes or skin
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
change in appetite
mood changes, anxiety, depression, frustration, anger, or emotional outbursts
skin acne or brown spots on the face
Do not take this medicine with any of the following medications:
This medicine may also interact with the following medications:
barbiturates or benzodiazepines used for inducing sleep or treating seizures (convulsions)
medicines for fungal infections like ketoconazole and itraconazole
raloxifene or tamoxifen
rifabutin, rifampin, or rifapentine
some antibiotics used to treat infections
St. John's Wort
This does not apply.
This drug is given in a hospital or clinic and will not be stored at home.
They need to know if you have any of these conditions:
blood vessel disease, blood clotting disorder, or suffered a stroke
breast, cervical, endometrial, ovarian or uterine cancer
high blood levels of calcium
protein C deficiency
protein S deficiency
an unusual or allergic reaction to estrogens, other hormones, medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
This medicine can make your body retain fluid, making your fingers, hands, or ankles swell. Your blood pressure can go up. Contact your doctor or health care professional if you feel you are retaining fluid.
If you have any reason to think you are pregnant, stop taking this medicine right away and contact your doctor or health care professional.
Smoking increases the risk of getting a blood clot or having a stroke while you are taking this medicine, especially if you are more than 35 years old. You are strongly advised not to smoke.
If you are going to have surgery, you may need to stop taking this medicine. Consult your health care professional for advice before you schedule the surgery.