LEVOTHYROXINE sodium (lee voe thye ROX een) and LIOTHYRONINE sodium (lye oh THYE roe neen), also known as Liotrix, is a combination of 2 thyroid hormones. This medicine can improve symptoms of thyroid deficiency such as slow speech, lack of energy, weight gain, hair loss, dry skin, and feeling cold. It also helps to treat goiter (an enlarged thyroid gland). It is also used to treat some kinds of thyroid cancer along with surgery and other medicines.
Take this medicine by mouth with a full glass of water. Follow the directions on the prescription label. It is best to take on an empty stomach, at least 30 minutes before or 2 hours after food. Take your doses at regular intervals. Do not take your medication more often than directed.
Talk to your pediatrician regarding the use of this medicine in children. While this medicine may be prescribed for children for selected conditions, precautions do apply.
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
changes in menstrual periods
excessive sweating or intolerance to heat
fast or irregular heartbeat
swelling of ankles, feet, or legs
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
changes in appetite
certain medicines for depression
certain medicines to treat cancer
female hormones, like estrogens or progestins and birth control pills, patches, rings, or injections
liquid nutrition products like Ensure
medicines for colds and breathing difficulties
medicines for diabetes
medicines or dietary supplements for weight loss
phenobarbital or other barbiturates
steroid medicines like prednisone or cortisone
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
Keep out of the reach of children.
Store tablets in the refrigerator between 2 and 8 degrees C (36 and 46 degrees F). Keep container tightly closed. Protect from light. Throw away any unused medicine after the expiration date.
They need to know if you have any of these conditions:
Addison's disease or other adrenal gland problem
dieting or on a weight loss program
pituitary gland problem
take medicines that treat or prevent blood clots
an unusual or allergic reaction to levothyroxine, liothyronine, other thyroid hormones, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
Do not switch brands of this medicine unless your health care professional agrees with the change. Ask questions if you are uncertain.
You will need regular exams and occasional blood tests to check the response to treatment. If you are receiving this medicine for an underactive thyroid, it may be several weeks before you notice an improvement. Check with your doctor or health care professional if your symptoms do not improve.
It may be necessary for you to take this medicine for the rest of your life. Do not stop using this medicine unless your doctor or health care professional advises you to.
This medicine can affect blood sugar levels. If you have diabetes, check your blood sugar as directed.
You may lose some of your hair when you first start treatment. With time, this usually corrects itself.