ALLOPURINOL (al oh PURE i nole) reduces the amount of uric acid the body makes during chemotherapy. Too much uric acid in the blood can cause damage to your kidneys.
The medicine is for infusion into a vein. It is given by a health care professional in a hospital or clinic setting.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
fever with rash, swollen lymph nodes, or swelling of the face
redness, blistering, peeling or loosening of the skin, including inside the mouth
signs and symptoms of infection like fever or chills; cough; sore throat
signs and symptoms of kidney injury like trouble passing urine or change in the amount of urine, flank pain
tingling, numbness in the hands or feet
unusual bleeding or bruising
unusually weak or tired
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
changes in taste
Do not take this medicine with the following medication:
This medicine may also interact with the following medications:
certain antibiotics like amoxicillin, ampicillin
certain medicines for cancer
certain medicines for immunosuppression like azathioprine, cyclosporine, mercaptopurine
thiazide diuretics, like hydrochlorothiazide
This does not apply.
This drug is given in a hospital or clinic and will not be stored at home.
They need to know if you have any of these conditions:
an unusual or allergic reaction to allopurinol, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
Your condition will be monitored carefully while you are receiving this medicine.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells.
Drink plenty of water while you are taking this medicine. This will help to reduce the risk of getting gout or kidney stones.