OLANZAPINE (oh LAN za peen) is used to treat schizophrenia, psychotic disorders, and bipolar disorder. Bipolar disorder is also known as manic-depression.
Take this medicine by mouth. Swallow it with a drink of water. Follow the directions on the prescription label. Take your medicine at regular intervals. Do not take it more often than directed. Do not stop taking except on the advice of your doctor or health care professional.
A special MedGuide will be given to you by the pharmacist with each new prescription and refill. Be sure to read this information carefully each time.
Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 13 years for selected conditions, precautions do apply.
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
difficulty in speaking or swallowing
excessive thirst and/or hunger
fast heartbeat (palpitations)
fever or chills, sore throat
fever with rash, swollen lymph nodes, or swelling of the face
frequently needing to urinate
inability to control muscle movements in the face, hands, arms, or legs
painful or prolonged erections
redness, blistering, peeling or loosening of the skin, including inside the mouth
restlessness or need to keep moving
tremors or trembling
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
changes in sexual desire
lowered blood pressure
Do not take this medicine with any of the following medications:
certain antibiotics like grepafloxacin and sparfloxacin
certain phenothiazines like chlorpromazine, mesoridazine, and thioridazine
This medicine may also interact with the following medications:
levodopa and other medicines for Parkinson's disease
medicines for diabetes
medicines for high blood pressure
medicines for mental depression, anxiety, other mood disorders, or sleeping problems
tobacco from cigarettes
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
Keep out of the reach of children.
Store at controlled room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from light and moisture. Throw away any unused medicine after the expiration date.
They need to know if you have any of these conditions:
breast cancer or history of breast cancer
diabetes mellitus, high blood sugar or a family history of diabetes
heart disease, irregular heartbeat, or previous heart attack
history of brain tumor or head injury
kidney or liver disease
low blood pressure or dizziness when standing up
suicidal thoughts, plans, or attempt by you or a family member
an unusual or allergic reaction to olanzapine, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
Visit your doctor or health care professional for regular checks on your progress. It may be several weeks before you see the full effects of this medicine. Notify your doctor or health care professional if your symptoms get worse, if you have new symptoms, if you are having an unusual effect from this medicine, or if you feel out of control, very discouraged or think you might harm yourself or others.
Do not suddenly stop taking this medicine. You may need to gradually reduce the dose. Ask your doctor or health care professional for advice.
You may get dizzy or drowsy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells.
Avoid alcoholic drinks. Alcohol can increase dizziness and drowsiness with olanzapine.
Do not treat yourself for colds, diarrhea or allergies without asking your doctor or health care professional for advice. Some ingredients can increase possible side effects.
Your mouth may get dry. Chewing sugarless gum or sucking hard candy, and drinking plenty of water will help.
This medicine can reduce the response of your body to heat or cold. Dress warm in cold weather and stay hydrated in hot weather. If possible, avoid extreme temperatures like saunas, hot tubs, very hot or cold showers, or activities that can cause dehydration such as vigorous exercise.
If you notice an increased hunger or thirst, different from your normal hunger or thirst, or if you find that you have to urinate more frequently, you should contact your health care provider as soon as possible. You may need to have your blood sugar monitored. This medicine may cause changes in your blood sugar levels. You should monitor you blood sugar frequently if you have diabetes.
If you smoke, tell your doctor if you notice this medicine is not working well for you. Talk to your doctor if you are a smoker or if you decide to stop smoking.