CHLORPHENIRAMINE; DIHYDROCODEINE; PSEUDOEPHEDRINE (klor fen IR a meen; dye hye droe KOE deen; soo doe e FED rin) is an antihistamine, cough suppressant, and decongestant combination. It is used to treat the cough and congestion of colds and other respiratory infections. It is also used to treat the symptoms of allergy. This medicine will not treat an infection.
Take this medicine by mouth. Follow the directions on the prescription label. Use a specially marked spoon or container to measure each dose. Ask your pharmacist if you do not have one. Household spoons are not accurate. Take your medicine at regular intervals. Do not take it more often than directed.
Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 2 years old for selected conditions, precautions do apply. Do not give this medicine to children under 2 years old.
Patients over 60 years old may have a stronger reaction and need a smaller dose.
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
changes in emotions or moods
changes in vision
fast, irregular heartbeat
feeling faint or lightheaded, falls
high or low blood pressure
trouble passing urine or change in the amount of urine
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
dry mouth, nose, or throat
loss of appetite
Do not take this medicine with any of the following medications:
certain medicines for anxiety or sleep
certain medicines for depression like amitriptyline, fluoxetine, sertraline
certain medicines for seizures like phenobarbital, primidone
ergot alkaloids like dihydroergotamine, ergonovine, ergotamine, methylergonovine
general anesthetics like halothane, isoflurane, methoxyflurane, propofol
local anesthetics like lidocaine, pramoxine, tetracaine
MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
medicines that relax muscles for surgery
other antihistamines for allergy, cough and cold
other narcotic medicines for pain or cough
phenothiazines like chlorpromazine, mesoridazine, prochlorperazine, thioridazine
This medicine may also interact with the following medications:
antiviral medicines for HIV or AIDS
certain medicines for bladder problems like oxybutynin, tolterodine
certain medicines for blood pressure, heart disease, irregular heart beat
certain medicines for Parkinson's disease like benztropine, trihexyphenidyl
certain medicines for stomach problems like dicyclomine, hyoscyamine
certain medicines for travel sickness like scopolamine
stimulant medicines for attention disorders, weight loss, or to stay awake
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
Keep out of the reach of children. This medicine can be abused. Keep your medicine in a safe place to protect it from theft. Do not share this medicine with anyone. Selling or giving away this medicine is dangerous and against the law.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from light. Throw away any unused medicine after the expiration date.
They need to know if you have any of these conditions:
drug abuse or addiction
high blood pressure
if you have taken an MAOI like Carbex, Eldepryl, Marplan, Nardil, or Parnate in last 14 days
lung or breathing disease, like asthma
trouble passing urine
an unusual or allergic reaction to chlorpheniramine, codeine, dihydrocodeine, hydrocodone, pseudoephedrine, other medicines, foods, dyes or preservatives
pregnant or trying to get pregnant
Use exactly as directed by your doctor or health care professional. Do not take more than the recommended dose. You may develop tolerance to this medicine if you take it for a long time. Tolerance means that you will get less cough relief with time. Tell your doctor or health care professional if your symptoms do not start to get better or if they get worse.
If you have been taking this medicine for a long time, do not suddenly stop taking it because you may develop a severe reaction. Your body becomes used to the medicine. This does NOT mean you are addicted. Addiction is a behavior related to getting and using a drug for a nonmedical reason. If your doctor wants you to stop the medicine, the dose will be slowly lowered over time to avoid any side effects.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.
Children may be at higher risk for side effects. If your child has slow breathing, noisy breathing, confusion, or unusual sleepiness, stop giving this medicine and get medical help right away.
Your mouth may get dry. Chewing sugarless gum or sucking hard candy, and drinking plenty of water may help. Contact your doctor if the problem does not go away or is severe.
This medicine may cause dry eyes and blurred vision. If you wear contact lenses you may feel some discomfort. Lubricating drops may help. See your eye doctor if the problem does not go away or is severe.