FLUOXETINE (floo OX e teen) belongs to a class of drugs known as selective serotonin reuptake inhibitors (SSRIs). It is used for premenstrual dysphoric disorder (PMDD). PMDD causes intense mood and physical symptoms a week or two before your period every month. This drug helps improve mood swings, tiredness, tension, and breast tenderness.
Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. You can take it with or without food. Take your medicine at regular intervals. Do not take it more often than directed. Do not stop taking this medicine suddenly except upon the advice of your doctor. Stopping this medicine too quickly may cause serious side effects or your condition may worsen.
A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
black, tarry stools
changes in vision
elevated mood, decreased need for sleep, racing thoughts, impulsive behavior
fast, irregular heartbeat
feeling faint or lightheaded, falls
feeling agitated, angry, or irritable
hallucination, loss of contact with reality
loss of balance or coordination
loss of memory
restlessness, pacing, inability to keep still
suicidal thoughts or other mood changes
unusual bleeding or bruising
unusually weak or tired
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
change in appetite or weight
change in sex drive or performance
Do not take this medicine with any of the following medications:
other medicines containing fluoxetine, like Prozac or Symbyax
MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
methylene blue (injected into a vein)
This medicine may also interact with the following medications:
aspirin and aspirin-like medicines
certain medicines for depression, anxiety, or psychotic disturbances
certain medicines for migraine headaches like almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan, sumatriptan, zolmitriptan
medicines for sleep
medicines that treat or prevent blood clots like warfarin, enoxaparin, and dalteparin
NSAIDs, medicines for pain and inflammation, like ibuprofen or naproxen
other medicines that prolong the QT interval (an abnormal heart rhythm)
supplements like St. John's wort, kava kava, valerian
If you miss a dose, skip the missed dose and go back to your regular dosing schedule. Do not take double or extra doses.
Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.
They need to know if you have any of these conditions:
bipolar disorder or a family history of bipolar disorder
low levels of sodium in the blood
suicidal thoughts, plans, or attempt; a previous suicide attempt by you or a family member
take MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
take medicines that treat or prevent blood clots
an unusual or allergic reaction to fluoxetine, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
Tell your doctor if your symptoms do not get better or if they get worse. Visit your doctor or health care professional for regular checks on your progress.
Patients and their families should watch out for new or worsening thoughts of suicide or depression. Also watch out for sudden changes in feelings such as feeling anxious, agitated, panicky, irritable, hostile, aggressive, impulsive, severely restless, overly excited and hyperactive, or not being able to sleep. If this happens, especially at the beginning of treatment or after a change in dose, call your health care professional.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.
Your mouth may get dry. Chewing sugarless gum or sucking hard candy, and drinking plenty of water may help. Contact your doctor if the problem does not go away or is severe.
This medicine may affect blood sugar levels. If you have diabetes, check with your doctor or health care professional before you change your diet or the dose of your diabetic medicine.