DISOPYRAMIDE (dye soe PEER a mide) is an antiarrhythmic drug. It helps make your heart beat regularly. This medicine also helps to slow rapid heartbeats.
Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Do not cut, crush or chew this medicine. Take your doses at regular intervals. Do not take your medicine more often than directed. Do not stop taking this medicine suddenly. This may cause serious, heart-related side effects. Your doctor will tell you how much medicine to take. If your doctor wants you to stop the medicine, the dose will be slowly lowered over time to avoid any side effects.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
cool, pale skin
fast, irregular heartbeat
feeling faint or lightheaded
fever, chills, or sore throat
swelling of feet or legs
trouble passing urine or change in the amount of urine
unusually weak or tired
unusual weight gain
yellowing of the eyes or skin
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
change in sex drive or performance
constipation or diarrhea
stomach pain or bloating
Do not take this medicine with any of the following medications:
antivirals for HIV or AIDS
certain antibiotics like clarithromycin, erythromycin, pentamidine
certain medicines for depression like maprotiline, tricyclic antidepressants
certain medicines for fungal infections like fluconazole, itraconazole, ketoconazole, posaconazole, voriconazole
certain medicines for malaria like chloroquine, halofantrine
other medicines for irregular heart beat like dofetilide, dronedarone
phenothiazines like chlorpromazine, mesoridazine, thioridazine
This medicine may also interact with the following medications:
certain medicines for blood pressure or heart disease like beta-blockers
certain medicines for seizures like carbamazepine, phenytoin, phenobarbital
other medicines that prolong the QT interval (cause an abnormal heart rhythm)
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.
They need to know if you have any of these conditions:
difficulty passing urine
heart disease or previous heart attack
low blood pressure
an unusual or allergic reaction to disopyramide, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
Check your heart rate and blood pressure regularly while you are taking this medicine. Ask your doctor or health care professional what your heart rate and blood pressure should be, and when you should contact him or her. Your doctor or health care professional also may schedule regular tests to check your progress.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.
Your mouth may get dry. Chewing sugarless gum or sucking hard candy, and drinking plenty of water may help. Contact your doctor if the problem does not go away or is severe.
This medicine may cause dry eyes and blurred vision. If you wear contact lenses you may feel some discomfort. Lubricating drops may help. See your eye doctor if the problem does not go away or is severe.
Avoid extreme heat. This medicine can cause you to sweat less than normal. Your body temperature could increase to dangerous levels, which may lead to heat stroke.
This medicine may affect blood sugar levels. If you have diabetes, check with your doctor or health care professional before you change your diet or the dose of your diabetic medicine.