FOSAMPRENAVIR (FOS am pren a veer) is an antiretroviral medicine. It is used with other medicines to treat HIV. This medicine is not a cure for HIV. This medicine can lower, but not fully prevent, the risk of spreading HIV to others.
Take this medicine by mouth. Follow the directions on the prescription label. Shake well before using. Adults should take this medicine without food. Children should take this medicine with food. Use a specially marked spoon or dropper to measure each dose. Ask your pharmacist if you do not have one. Household spoons are not accurate. If you vomit within 30 minutes of taking this medicine take another dose. Take your medicine at regular intervals. Do not take your medicine more often than directed. For your anti-HIV therapy to work as well as possible, take each dose exactly as prescribed. Do not skip doses or stop your medicine even if you feel better. Skipping doses may make the HIV virus resistant to this medicine and other medicines. Do not stop taking except on your doctor's advice.
Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 4 weeks old for selected conditions, precautions do apply.
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
redness, blistering, peeling or loosening of the skin, including inside the mouth
signs and symptoms of high blood sugar such as being more thirsty or hungry or having to urinate more than normal. You may also feel very tired or have blurry vision.
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
weight gain around waist, back, or thinning of face, arms, legs
Do not take this medicine with any of the following medications:
female hormones, like estrogens or progestins and birth control pills, patches, rings, or injections
medicines for headaches like dihydroergotamine, ergonovine, ergotamine, methylergonovine
medicines for high cholesterol like atorvastatin, lovastatin, rosuvastatin, simvastatin
red yeast rice
St. John's wort
vitamin E supplements
This medicine may also interact with the following medications:
medicines for depression, anxiety, or psychotic disturbances like lurasidone and quetiapine
medicines for erectile dysfunction like sildenafil
medicines for fungal infections like ketoconazole and itraconazole
medicines for irregular heart beat like amiodarone, dofetilide, lidocaine, quinidine
medicines for blood pressure like amlodipine, diltiazem, verapamil
medicines for seizures
medicines for stomach problems like cimetidine, famotidine, nizatidine, ranitidine
other medicines for HIV
If you miss a dose by more than 4 hours, wait and take the next dose at the regular time. But, if you miss a dose by less than 4 hours, take your missed dose right away. Then take your next dose at the regular time. Do not take double or extra doses.
Keep out of the reach of children.
Store at room temperature or in the refrigerator between 5 and 30 degrees C (41 and 86 degrees F). This medicine may taste better when cold. Do not freeze. Keep container tightly closed. Throw away any unused medicine after the expiration date.
They need to know if you have any of these conditions:
an unusual or allergic reaction to fosamprenavir, amprenavir, sulfa drugs, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
Visit your doctor or health care provider for regular check ups. Discuss any new symptoms with your doctor. You will need to have important blood work done while on this medicine.
HIV is spread to others through sexual or blood contact. Talk to your doctor about how to stop the spread of HIV.
Birth control pills, patches, rings, or injections may not work properly while you are taking this medicine. Talk to your doctor about using an extra method of birth control. Women who can still have children must use a reliable form of barrier contraception, like a condom or diaphragm.
This medicine may increase blood sugar. Ask your healthcare provider if changes in diet or medicines are needed if you have diabetes.