PROPAFENONE (proe pa FEEN one) is an antiarrhythmic agent. It is used to treat irregular heart rhythm and can slow rapid heartbeats. This medicine can help your heart to return to and maintain a normal rhythm.
Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. You can take this medicine with or without food. Take your doses at regular intervals. Do not take your medicine more often than directed. Do not stop taking except on the advice of your doctor or health care professional.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Side effects that you should report to your doctor or health care professional as soon as possible:
chest pain, palpitations
fever or chills
shortness of breath
swelling of feet or legs
trembling or shaking
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
changes in taste (a metallic or bitter taste)
constipation or diarrhea
nausea or vomiting
tiredness or weakness
Do not take this medicine with any of the following medications:
certain antibiotics like clarithromycin, erythromycin, grepafloxacin, pentamidine, sparfloxacin, troleandomycin
certain medicines for depression or mental illness like amoxapine, haloperidol, maprotiline, pimozide, sertindole, thioridazine, tricyclic antidepressants, ziprasidone
certain medicines for fungal infections like fluconazole, itraconazole, ketoconazole, posaconazole, voriconazole
certain medicines for irregular heart beat like dofetilide, dronedarone
certain medicines for malaria like chloroquine, halofantrine
This medicine may also interact with the following medications:
certain medicines for angina or blood pressure
certain medicines for asthma or breathing difficulties like formoterol, salmeterol
certain medicines that treat or prevent blood clots like warfarin
other medicines that prolong the QT interval (cause an abnormal heart rhythm)
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from light. Keep container tightly closed. Throw away any unused medicine after the expiration date.
They need to know if you have any of these conditions:
high blood levels of potassium
low blood pressure
lung disease like asthma, chronic bronchitis or emphysema
slow heart rate
an unusual or allergic reaction to propafenone, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
Your condition will be monitored closely when you first begin therapy. Often, this drug is first started in a hospital or other monitored health care setting. Once you are on maintenance therapy, visit your doctor or health care professional for regular checks on your progress. Because your condition and use of this medicine carry some risk, it is a good idea to carry an identification card, necklace or bracelet with details of your condition, medications, and doctor or health care professional.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells.
If you are going to have surgery, tell your doctor or health care professional that you are taking this medicine.