SPIRONOLACTONE (speer on oh LAK tone) is a diuretic. It helps you make more urine and to lose excess water from your body. This medicine is used to treat high blood pressure, and edema or swelling from heart, kidney, or liver disease. It is also used to treat patients who make too much aldosterone or have low potassium.
Take this medicine by mouth with a drink of water. Follow the directions on your prescription label. You can take it with or without food. If it upsets your stomach, take it with food. Do not take your medicine more often than directed. Remember that you will need to pass more urine after taking this medicine. Do not take your doses at a time of day that will cause you problems. Do not take at bedtime.
Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for selected conditions, precautions do apply.
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions such as skin rash or itching, hives, swelling of the lips, mouth, tongue, or throat
black or tarry stools
fast, irregular heartbeat
muscle pain, cramps
numbness, tingling in hands or feet
trouble passing urine
unusually weak or tired
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
change in voice or hair growth
dry mouth, increased thirst
enlarged or tender breasts
irregular menstrual periods
sexual difficulty, unable to have an erection
Do not take this medicine with any of the following medications:
This medicine may also interact with the following medications:
certain medicines for blood pressure or heart disease like benazepril, lisinopril, losartan, valsartan
certain medicines that treat or prevent blood clots like heparin and enoxaparin
medicines that relax muscles for surgery
NSAIDs, medicines for pain and inflammation, like ibuprofen or naproxen
steroid medicines like prednisone or cortisone
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
Keep out of the reach of children.
Store below 25 degrees C (77 degrees F). Throw away any unused medicine after the expiration date.
They need to know if you have any of these conditions:
high blood level of potassium
kidney disease or trouble making urine
an unusual or allergic reaction to spironolactone, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
Visit your doctor or health care professional for regular checks on your progress. Check your blood pressure as directed. Ask your doctor what your blood pressure should be, and when you should contact them.
You may need to be on a special diet while taking this medicine. Ask your doctor. Also, ask how many glasses of fluid you need to drink a day. You must not get dehydrated.
This medicine may make you feel confused, dizzy or lightheaded. Drinking alcohol and taking some medicines can make this worse. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not sit or stand up quickly.