EXENATIDE (ex EN a tide) is used to improve blood sugar control in adults with type 2 diabetes. This medicine may be used with other oral diabetes medicines.
This medicine is for injection under the skin of your upper leg, stomach area, or upper arm. You will be taught how to prepare and give this medicine. Use exactly as directed. Take your medicine at regular intervals. Do not take it more often than directed.
It is important that you put your used needles and syringes in a special sharps container. Do not put them in a trash can. If you do not have a sharps container, call your pharmacist or healthcare provider to get one.
A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
signs and symptoms of low blood sugar such as feeling anxious, confusion, dizziness, increased hunger, unusually weak or tired, sweating, shakiness, cold, irritable, headache, blurred vision, fast heartbeat, loss of consciousness
swelling of the ankles, feet, hands
trouble passing urine or change in the amount of urine
unusual bleeding or bruising
unusual stomach pain or upset
unusually weak or tired
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
birth control pills
insulin and other medicines for diabetes
Many medications may cause changes in blood sugar, these include:
alcohol containing beverages
antiviral medicines for HIV or AIDS
aspirin and aspirin-like drugs
certain medicines for blood pressure, heart disease, irregular heart beat
female hormones, such as estrogens or progestins, birth control pills
male hormones or anabolic steroids
MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
medicines for weight loss
medicines for allergies, asthma, cold, or cough
medicines for depression, anxiety, or psychotic disturbances
NSAIDs, medicines for pain and inflammation, like ibuprofen or naproxen
quinolone antibiotics such as ciprofloxacin, levofloxacin, ofloxacin
some herbal dietary supplements
steroid medicines such as prednisone or cortisone
Some medications can hide the warning symptoms of low blood sugar (hypoglycemia). You may need to monitor your blood sugar more closely if you are taking one of these medications. These include:
beta-blockers, often used for high blood pressure or heart problems (examples include atenolol, metoprolol, propranolol)
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
Keep out of the reach of children.
Store unopened pen in a refrigerator between 2 and 8 degrees C (36 and 46 degrees F). Do not freeze or use if the medicine has been frozen. Protect from light and excessive heat. After you first use the pen, it should be kept at a temperature not to exceed 25 degrees C (77 degrees F). Throw away your used pen after 30 days or after the expiration date, whichever comes first.
Do not store your pen with the needle attached. If the needle is left on, medicine may leak from the pen or air bubbles may form in the cartridge.
They need to know if you have any of these conditions:
history of pancreatitis
kidney disease or if you are on dialysis
low blood counts, like platelets
stomach or intestine problems
an unusual or allergic reaction to exenatide, medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
Visit your doctor or health care professional for regular checks on your progress.
A test called the HbA1C (A1C) will be monitored. This is a simple blood test. It measures your blood sugar control over the last 2 to 3 months. You will receive this test every 3 to 6 months.
Learn how to check your blood sugar. Learn the symptoms of low and high blood sugar and how to manage them.
Always carry a quick-source of sugar with you in case you have symptoms of low blood sugar. Examples include hard sugar candy or glucose tablets. Make sure others know that you can choke if you eat or drink when you develop serious symptoms of low blood sugar, such as seizures or unconsciousness. They must get medical help at once.
Tell your doctor or health care professional if you have high blood sugar. You might need to change the dose of your medicine. If you are sick or exercising more than usual, you might need to change the dose of your medicine.
Do not skip meals. Ask your doctor or health care professional if you should avoid alcohol. Many nonprescription cough and cold products contain sugar or alcohol. These can affect blood sugar.
Pens and cartridges should never be shared. Even if the needle is changed, sharing may result in passing of viruses like hepatitis or HIV.
Wear a medical ID bracelet or chain, and carry a card that describes your disease and details of your medicine and dosage times.