Multiple sclerosis (MS) is a chronic disease of the central nervous system, which is made up of the brain and spinal cord. MS is unpredictable. It can range from benign to disabling. Some people with MS may be mildly affected. Others may lose the ability to write, speak, or walk.
Many things may cause MS, including viruses, autoimmune disorders, environmental factors, and genetic factors. But all of the possible causes share a common feature. The body's immune system attacks its own nervous tissue. In MS, the immune system attacks the layer of protein called myelin that surrounds the nerve fibers in the central nervous system. Myelin insulates the electrical signals the nervous system uses to communicate. When this insulation is destroyed, communication is interrupted. Parts of the nervous system become permanently damaged.
Symptoms of MS are erratic. They may be mild or severe. They may last a short or long time. They may appear in various combinations, depending on the part of the nervous system affected. Throughout the course of the illness, you may have any or all of these symptoms:
Muscle weakness in the arms and legs
Trouble with coordination
Impaired walking or standing
Partial or complete paralysis
Spasticity (involuntary increased tone of muscles leading to stiffness and spasms)
Fatigue (may be triggered by physical activity, may ease with rest, or may be constant and persistent)
Loss of sensation, tingling or numbness
Loss of vision or changes in vision
Loss of bowel and bladder control
Changes in reflexes
MS may also cause cognitive effects. The effects may be mild. They are often found only after thorough testing. They may include problems with:
The symptoms of MS may look like other health problems. Always see your healthcare provider for a diagnosis.
Your healthcare provider will do a thorough medical history and a physical exam as the first steps toward diagnosis of MS. You will be asked about all of your symptoms, how often they occur and how long they last.
You will likely have an MRI (magnetic resonance imaging) scan. This test can detect the unique scars in the central nervous system.
In some cases, you may need lab tests or a lumbar puncture to confirm the diagnosis.
There is no cure for MS. But there are disease-modifying therapies available that can slow the progression of the disease and improve symptoms. These include:
There are also treatments to help manage symptoms, treat flare-ups or relapses, improve your function and safety, and provide much needed emotional support. The following
rehabilitation therapies may also help:
Speech and swallowing assistance
Assistive devices like splints
Fortunately, pregnancy does not appear to speed up the course or worsen the effects of MS. Several studies suggest that MS is less likely to flare up late in pregnancy. But there is a slightly higher risk right after pregnancy.
The disabling effects of the disease may make it physically hard to carry a pregnancy. Muscle weakness and coordination problems may increase the likelihood for falls. Fatigue may worsen. Wheelchair dependence may increase the risk for urinary tract infections. There is no evidence that MS causes infertility. Studies have shown that pregnancy, delivery, and rate of birth defects are not majorly different in women with MS compared with those without MS.
Many of the medicines used to treat MS may have adverse effects on a fetus. It is important to talk with your healthcare provider if you are thinking about pregnancy or if you become pregnant. Your healthcare provider will discuss the risks and benefits of the various medicines with you, including any possible effects on your baby and your MS.
During pregnancy, you will need close monitoring to keep track of the disease and the health of the fetus. You may need more frequent prenatal visits. There is no established treatment that alters the course of MS. But you may be given medicines such as steroids and anti-inflammatory drugs. Consult your healthcare provider for more information.
Supportive treatment and rehabilitation for MS are especially important during pregnancy. Rehab varies depending on your symptoms. But it may help with the following:
Doing normal activities of daily living (ADLs)
Getting family involved
Using assistive devices (for example, canes, braces, and walkers)
Setting an appropriate exercise program to promote muscle strength, endurance, and control
Re-establishing motor skills
Improving communication skills if you have trouble speaking because of weakness or lack of coordination of face and tongue muscles
Managing bowel or bladder incontinence
Providing cognitive retraining
Adapting the home environment for safety and usability
During labor, you may not have pelvic sensation, and you may not feel pain with contractions. This may also make it hard to tell when labor starts. Delivery of the baby may be harder if you have MS. While labor itself is not affected, MS can affect the muscles and nerves needed for pushing. For this reason, you may need a cesarean section or delivery with the help of forceps or vacuum.
Call your healthcare provider if you have several of the classic symptoms of MS so that treatment can begin right away.
If you have MS and want to get pregnant, discuss the benefits and risks of a pregnancy with your MS specialist before becoming pregnant.
If you are pregnant and have MS, tell your healthcare provider as soon as possible.
There is no cure for MS. But there are many ways to help slow the progression of the disease and manage symptoms.
With MS, you may have long periods of remission of your symptoms.
Pregnancy is not ruled out just because you have MS. Pregnancy doesn't seem to speed up or worsen MS.
MS can make carrying a pregnancy harder. It may also make labor and delivery more difficult.
Tips to help you get the most from a visit to your healthcare provider:
Know the reason for your visit and what you want to happen.
Before your visit, write down questions you want answered.
Bring someone with you to help you ask questions and remember what your provider tells you.
At the visit, write down the name of a new diagnosis, and any new medicines, treatments, or tests. Also write down any new instructions your provider gives you.
Know why a new medicine or treatment is prescribed, and how it will help you. Also know what the side effects are.
Ask if your condition can be treated in other ways.
Know why a test or procedure is recommended and what the results could mean.
Know what to expect if you do not take the medicine or have the test or procedure.
If you have a follow-up appointment, write down the date, time, and purpose for that visit.
Know how you can contact your provider if you have questions.