DEXRAZOXANE (dex ray ZOX ane) is used to protect against heart damage caused by certain chemotherapy. It is also used to prevent tissue injury from certain chemotherapy leaks.
This medicine is for injection or infusion into a vein. It is given by a health care professional in a hospital or clinic setting. This medicine is given just before you are given your chemotherapy medicine.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
feeling faint or lightheaded, falls
low blood counts - this medicine may decrease the number of white blood cells, red blood cells and platelets. You may be at increased risk for infections and bleeding
signs of decreased platelets or bleeding - bruising, pinpoint red spots on the skin, black, tarry stools, blood in the urine
signs of infection - fever or chills, cough, sore throat, pain or difficulty passing urine
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
pain, redness, or irritation at site where injected
This medicine may interact with the following medications:
Topical dimethyl sulfoxide (when used to treat extravasation)
This does not apply.
This drug is given in a hospital or clinic and will not be stored at home.
They need to know if you have any of these conditions:
an unusual or allergic reaction to dexrazoxane, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
You may need blood work done while you are taking this medicine.
Do not become pregnant while taking this medicine or for 6 months after stopping it. Women should inform their doctor if they wish to become pregnant or think they might be pregnant. Men should not father a child while taking this medicine and for 3 months after stopping it. There is a potential for serious side effects to an unborn child. Talk to your health care professional or pharmacist for more information. Do not breast-feed an infant while taking this medicine or for 2 weeks after stopping it.
This may interfere with the ability to father a child. You should talk to your doctor or health care professional if you are concerned about your fertility.