DELAVIRDINE (de la VIR deen) is an antiretroviral medicine. It is used with other medicines to treat HIV. This medicine is not a cure for HIV. This medicine can lower, but not fully prevent, the risk of spreading HIV to others.
Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. This medicine can be taken with or without food. If you have a hard time swallowing this medicine, the 100 mg tablets can be dissolved in water. Ask your pharmacist for instructions. Take your medicine at regular intervals. Do not take your medicine more often than directed. For your anti-HIV therapy to work as well as possible, take each dose exactly as prescribed. Do not skip doses or stop your medicine even if you feel better. Skipping doses may make the HIV virus resistant to this medicine and other medicines. Do not stop taking except on your doctor's advice.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
general ill feeling or flu-like symptoms
loss of appetite, nausea
muscle pain or weakness
redness, blistering, peeling or loosening of the skin, including inside the mouth
right upper belly pain
trouble passing urine or change in the amount of urine
unusually weak or tired
yellowing of the eyes or skin
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
weight gain around waist, back, or thinning of face, arms, legs
Do not take this medicine with any of the following medications:
certain medicines for cholesterol like lovastatin, simvastatin
certain medicines for irregular heart beat like dofetilide, encainide, flecainide
certain medicines for seizures like carbamazepine, fosphenytoin, phenobarbital, phenytoin
medicines for headaches like dihydroergotamine, ergonovine, ergotamine, methylergonovine
red yeast rice
St. John's wort
This medicine may also interact with the following medications:
female hormones, like estrogens or progestins and birth control pills, patches, rings, or injections
medicines for blood pressure, heart disease, or irregular heart beat
medicines for depression, anxiety, or psychotic disturbances
medicines for erectile dysfunction
medicines for sleep
medicines that decrease stomach acid like antacids, cimetidine, famotidine, omeprazole, lansoprazole
other medicines for HIV
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
Keep out of the reach of children.
Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Protect from moisture. Throw away any unused medicine after the expiration date.
They need to know if you have any of these conditions:
an unusual or allergic reaction to delavirdine, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
Visit your doctor or health care professional for regular check ups. Discuss any new symptoms with your doctor. You will need to have important blood work done while on this medicine.
HIV is spread to others through sexual or blood contact. Talk to your doctor about how to stop the spread of HIV.
Birth control pills may not work properly while you are taking this medicine. Talk to your doctor about using an extra method of birth control. Women who can still have children must use a reliable form of barrier contraception, like a condom or diaphragm.
Avoid taking any antacids or acid blockers within 1 hour of taking this medicine.