LOVASTATIN; NIACIN (LOE va sta tin; nye a SIN) is used in combination with a healthy diet to lower bad cholesterol and increase good cholesterol.
Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Swallow whole. Do not crush, break, or chew the tablet. It should be taken in the evening with a low-fat snack. Do not take this medicine with grapefruit juice, hot beverages, or alcohol-containing beverages. Take your doses at regular intervals. Do not take your medicine more often than directed. If you also take cholestyramine or colestipol to lower your cholesterol, you should take this medicine at least 1 hour before or 4 hours after a dose of these medications. If skin flushing (skin warmth, redness) becomes a problem, ask your doctor for advice.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Side effects that you should report to your doctor or health care professional as soon as possible:
chest pain or palpitations
dark yellow or brown urine
decreased urination, difficulty passing urine
dizziness that does not go away or fainting spells
fever or chills
increased blood sugar, especially if you have diabetes
skin rash, hives, peeling or itching of the skin
stomach pain, loss of appetite
swelling of the body ( legs, ankles, arms)
unexplained muscle pain, tenderness, cramps, or weakness
unusual or severe tiredness or weakness
yellowing of the skin or eyes
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
decreased sexual function or desire
diarrhea or constipation
flushing, warmth, and burning or tingling of the skin
stomach upset, discomfort, or bloating
Do not take this medicine with any of the following medications:
certain antibiotics like erythromycin, clarithromycin, and telithromycin
certain antiviral medicines for HIV or AIDS
medicines for fungal infections like itraconazole, ketoconazole, or posaconazole
other niacin products
red yeast rice
This medicine may also interact with the following medications:
cholestyramine or colestipol
medicines for diabetes
medicines for high blood pressure or heart disease
nitroglycerin or nitrates like amyl nitrate, isosorbide dinitrate, isosorbide mononitrate
other cholesterol medicines like gemfibrozil, fenofibrate or clofibrate
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
Keep out of the reach of children.
Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Throw away any unused medicine after the expiration date.
They need to know if you have any of these conditions:
frequently drink alcoholic beverages
kidney or liver disease
low blood counts, low platelets, or bleeding problems
muscle aches or weakness
other medical condition
ulcers of intestine or stomach
an unusual or allergic reaction to lovastatin, niacin, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
Visit your doctor or health care professional for regular checks on your progress. You will need to have regular tests to make sure your liver is working properly.
This medicine is only part of a total cholesterol-lowering program. Your physician or dietician can suggest a low-cholesterol and low-fat diet that will reduce your risk of getting heart and blood vessel disease. Avoid alcohol and smoking, and keep a proper exercise schedule.
Do not use this drug if you are pregnant or breast-feeding. Serious side effects to an unborn child or to an infant are possible. Talk to your doctor or pharmacist for more information.
Tell your doctor or health care professional as soon as you can if you get any unexplained muscle pain, tenderness, or weakness, especially if you also have a fever and tiredness. Your doctor or health care professional may tell you to stop taking this medicine if you develop muscle problems. If your muscle problems do not go away after stopping this medicine, contact your health care professional.
This medicine may affect blood sugar levels. If you have diabetes, check with your doctor or health care professional before you change your diet or the dose of your diabetic medicine.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this drug affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells.
Do not drink hot drinks or alcohol at the same time you take your medicine. Hot drinks and alcohol can increase the flushing caused by niacin, which can be uncomfortable. Alcohol also can increase possible dizziness.
If you are going to have surgery tell your doctor or health care professional that you are taking this medicine.
You may notice the empty shell of the tablet in your stool. This is no cause for concern.